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型号:
时间: 2017 - 01 - 24
Human IFN-γ1b, premium grade130-096-484产品说明Background informationIFN-γ, the only type II interferon, possesses potent anti-viral activity and immunoregulatory properties. It is structurally unrelated to the type I interferons and binds to a different receptor expressed by most immune cells. IFN-γ is produced predominantly by NK cells and T cells. IFN-γ enhances NK cell and macrophage activity and regulates B cell functions, like immunglobulin production and class switching. In addition, IFN-γ or...
型号:
时间: 2017 - 01 - 11
CD4+ Central Memory T Cell Isolation Kit, human130-094-302产品说明Central memory CD4+ T cells are isolated based on the expression of CD197 (CCR7) and the absence of CD45RA on these cells.Detailed separation procedureFor the first separation, non-target cells are labeled with a cocktail of biotin-conjugated antibodies against CD8, CD14, CD15, CD16, CD19, CD25, CD36, CD45RA, CD56, CD123, TCRγ/δ, and CD235a (Glycophorin A) and Anti-Biotin MicroBeads to deplete non-CD4+ T cells, naive CD4+ T cells and ...
型号:
时间: 2017 - 02 - 04
Anti-IFN-γ-FITC, human (clone: 45-15)130-097-936产品说明Alternative namesIFNg, IFG, IFIClone and isotypeCloneIsotype45-15mouse IgG1κCross reactivityThe antibody is tested to cross-react withRhesus monkey (Macaca mulatta)Cynomolgus monkey (Macaca fascicularis)相关图片Human peripheral blood mononuclear cells (PBMCs), either unstimulated (left images) or stimulated with SEB for six hours. After two hours, brefeldin A was added for stimulated and unstimulated cells. The cells were fixed, permeabilized, and ...
型号:
时间: 2017 - 01 - 24
Human SCF, premium grade130-096-695产品说明Background informationSCF is a hematopoietic growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and progenitor cells. Besides its pivotal role in mast cell development, SCF acts as a potent mast cell chemoattractant and upregulates mast cell adhesion and migration. SCF signals through the c-kit receptor (CD117) and exists in two forms; cell surface bound SCF and soluble SCF. The secreted soluble form of ...
型号:
时间: 2017 - 01 - 11
CD4+ Effector Memory T Cell Isolation Kit, human130-094-125产品说明Detailed separation procedureFor magnetic depletion of non-target cells, PBMCs are incubated with a cocktail of biotinylated antibodies against CD45RA, CD8, CD14, CD15, CD16, CD19, CD34, CD36, CD56, CD123, Anti-TCRγ/δ, and CD235a (glycophorin A) as well as APC-conjugated CD197 (CCR7) antibodies. In a second step, all antibody-labeled cells are labeled with MicroBead Cocktail for depletion. The CD4+Effector Memory T Cell Isolation Kit...
型号:
时间: 2017 - 02 - 04
CD73-PE, human (clone: AD2)130-097-943产品说明This glycoprotein is also called ecto-5’-nucleotidase. CD73 is present on subsets of T and B lymphozytes, follicular dendritic cells, endothelial cells, and marrow stromal cells (MSCs).Alternative namesNT5E, CALJA, E5NT, NT, Nt5, NTE, eN, eNTClone and isotypeCloneIsotypeAD2mouse IgG1κ相关图片Human peripheral blood mononuclear cells (PBMCs) were stained with CD73 antibodies or with the corresponding isotype control antibodies (left image) as well as with CD45...
型号:
时间: 2017 - 01 - 24
Human IL-12, premium grade130-096-705产品说明Background informationInterleukin 12 (IL-12) is a heterodimeric proinflammatory cytokine and a modulator of cell-mediated immunity, which is mainly produced by macrophages, dendritic cells, and B cells. IL-12 stimulates the production and secretion of several cytokines, in particular IFN-γ, by NK cells and T cells, induces proliferation, and enhances the cytotoxic activity within these cell populations. Another important activity of IL-12, acting together...
型号:
时间: 2017 - 01 - 11
CD4+ Recent Thymic Emigrant Isolation Kit, human130-094-299产品说明Background informationRTEs are a subpopulation of naive T cells characterized by their content of T cell receptor excision circles (TRECs).CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) has been described as a marker to identify the CD4+ RTEs among the naive CD4+ T cell population, as its expression correlates with the TREC content of CD4+ T cells1. CD4+ T cells lacking CD31 expression harbor little or no TRECs, sugges...
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