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产品名称: pHAb Reactive Dyes
型号:
时间: 2017 - 01 - 16
pHAb Amine Reactive Dye 1 × 250μg G9841pHAb Amine Reactive Dye 4 × 250μg G9845pHAb Thiol Reactive Dye 1 × 250μg G9831pHAb Thiol Reactive Dye 4 × 250μg G9835pHAb Amine活性染料具有生物素琥珀酰亚胺酯基团,能够与抗体中赖氨酸上的伯胺基反应(图1, A)。pHAb Thiol 活性染料具有马来酰亚胺基团,能够与硫醇反应。还原剂如DTT或TCEP处理抗体(图1,B),使抗体铰链区的半胱氨酸二硫键还原为硫醇后,这种马来酰亚胺基团能够与抗体结合。pHAb染料的关键特点是每个染料都有2个磺化基团,能够增加可溶性并降低非磺化染料常见的聚集现象。即使在与抗体结合后,pHAb染料仍保持有对pH变换的反应,如图1, C所示。虽然抗体标记是pHAb染料的主要的应用,但是任何带有赖氨酸伯胺基或者半胱氨酸硫醇的蛋白均可结合pHAb染料。特点 - 优点精准检测抗体内化:当溶液变为酸...
型号:
时间: 2017 - 01 - 16
ADCC Reporter Bioassay, Complete (Raji) 1 each G7015ADCC Reporter Bioassay, Complete (WIL2-S) 1 each G7014ADCC Reporter Bioassay, Core Kit 1 each G7010ADCC Reporter Bioassay, Target (Raji) 1 each G7016ADCC Reporter Bioassay, Target (WIL2-S) 1 each G7013Following engagement with the Fc region of a relevant antibody bound to a target disease cell, Fc receptors transduce intracellular signals within the effector cell resulting in elimination of the target cell. These primary cel...
型号:
时间: 2017 - 01 - 16
特点 - 优点Simplified Assay Optimization: Robust performance, improved storage and convenient size.Room Temperature or 4°C Storage: Extended stability of the Bio-Glo™ Reagent makes it more convenient for everyday use.Improved Assay Precision: The Bio-Glo™ Reagent is less sensitive to mixing and dispensing conditions, enhancing reproducibility. Ideal for bioassay applications.Brighter, Longer-Lasting Signal: Optimized for batch and continuous-process handling, the extended bright light output al...
型号:
时间: 2017 - 01 - 22
ISOQUANT® Kit 可用于多肽或蛋白,例如单克隆抗体。特点 - 优点• 高效:程序简单,检测时间在1 小时内。可使用HPLC 进行自动样本处理。• 经济:HPLC 检测,既节省成本,又免除了对放射性原料处理的麻烦。• 易分析:提供定量结果。• 用途广泛:既可单样本处理,也可批量处理。小型样本使分析结果适用于分析研究的方法、试剂配方及流程的改进工作。• 稳定:不受缓冲液成分的影响。• HPLC 检测方法:适用于现有的仪器与技术。• 灵敏:检测由于天冬氨酸重排及脱酰胺作用产生的异天冬氨酸。储存条件储存于-20℃。
型号:
时间: 2017 - 01 - 16
Following engagement with the Fc region of a relevant antibody bound to a target disease cell, Fc receptors transduce intracellular signals within the effector cell resulting in elimination of the target cell. These primary cell-based assays are highly variable as a result of donor differences and the requirement for cell culture and expansion.The ADCC Reporter Bioassay provides a biologically relevant and specific MOA-based measure of ADCC without the complex workflow and variability inherent i...
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